The underlying cause of male infertility is unknown for 30 percent of cases. In a pair of new studies, researchers have determined that the reproductive homeobox (RHOX) family of transcription factors -- regulatory proteins that activate some genes and inactivate others -- drive the development of stem cells in the testes in mice. The investigators also linked RHOX gene mutations to male infertility in humans.

The underlying cause of male infertility is unknown for 30 percent of cases. In a pair of new studies, researchers have determined that the reproductive homeobox (RHOX) family of transcription factors -- regulatory proteins that activate some genes and inactivate others -- drive the development of stem cells in the testes in mice. The investigators also linked RHOX gene mutations to male infertility in humans.

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Male chemistry primes females for reproduction -- but at a cost: Findings could…

Male chemistry primes females for reproduction -- but at a cost: Findings could…

It has been 20 years since Dolly the sheep was successfully cloned in Scotland, but cloning mammals remains a challenge. A new study of gene expression in developing clones now shows why most cloned embryos likely fail.

It has been 20 years since Dolly the sheep was successfully cloned in Scotland, but cloning mammals remains a challenge. A new study of gene expression in developing clones now shows why most cloned embryos likely fail.

Researchers find that chimpanzees are more likely to reproduce with mates whose genetic makeup most differs from their own. Many animals avoid breeding with parents, siblings and other close relatives, researchers say. But chimps are unusual in that even among virtual strangers they can tell genetically similar mates from more distant ones. Chimps are able to distinguish degrees of genetic similarity among unfamiliar mates many steps removed from them in their family tree.

Researchers find that chimpanzees are more likely to reproduce with mates whose genetic makeup most differs from their own. Many animals avoid breeding with parents, siblings and other close relatives, researchers say. But chimps are unusual in that even among virtual strangers they can tell genetically similar mates from more distant ones. Chimps are able to distinguish degrees of genetic similarity among unfamiliar mates many steps removed from them in their family tree.

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