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Delirium: Madness of Isaac by RahkshiChao on DeviantArt

Deliruim is the most awesome boss in TBoI and has the coolest design. Sure, the void could have gotten a better design and . Delirium: Madness of Isaac

I think this is my favourite gif of all time.

Even a quick slice through the cranium doesn’t stop the “Merc with a Mouth” Deadpool in artist Alex Griendling’s new animated Anatomy GIF. “This is by far the most complicated pixel gif I’ve made to.